MMP2 Antibody

SKU:BHA17102341
Suppliers
NSJ Bioreagents
NSJ Bioreagents
Details Products
Overview
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Anti-MMP2 monoclonal antibody (Mouse IgG2b, k, clone 6E3F8) for target detection, validation, and assay development. Reactivity: Human; ascites-derived reagent to support WB, IHC, and ELISA.
Target MMP2
Host Mouse
Isotype Mouse IgG2b, k
Reactivity Human
Application(s) WB, IHC, ELISA
Clone number 6E3F8
Options selector
Catalog no. Formulation Size
F53512-0.1ML In ascites with 0.09% sodium azide
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options (Formulation: In ascites with 0.09% sodium azide; Size: 0.1 ml)
  • Lead time: options listed as “In Stock at Manufacturer” typically ship after a short processing time (2–3 days). Timing may vary by fulfillment source.
  • Storage: Refer to the product datasheet for storage and handling.
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: follow the product datasheet storage instructions.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No F53512
Clonality
  • Monoclonal (mouse origin)
Host Mouse
Immunogen This MMP2 antibody was produced from mouse immunized with MMP2 recombinant protein.
Isotype
  • Mouse IgG2b
  • k
Product Type
  • Antibodies
  • Primary Antibodies
Purity Ascites
Reactivity
  • Human
Storage Aliquot the MMP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target MMP2
UniProt # P08253
Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14.

PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. [UniProt]

  • Format: Ascites

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today