| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 1-[[[(1R)-1-[3-(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]-methyl]-cyclopropaneacetic acid, monosodium salt, Montelukast sodium, Montelukast monosodium salt, MK-0476, MK-476, KS-1087 |
| Cas No. | |
| Form | Powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in DMSO (50 mg/ml), or water (30 mg/ml), or ethanol (60 mg/ml) |
| Source | Synthetic |
| Storage |
Montelukast sodium, a selective cysteinyl leukotriene receptor 1 (CysLT1) antagonist, is gaining attention in neuroscience for its neuroprotective and anti-inflammatory properties. Originally developed for asthma and allergic rhinitis, Montelukast has demonstrated the ability to cross the blood-brain barrier and modulate neuroinflammatory responses. In preclinical models, it has been shown to reduce blood-brain barrier disruption, inhibit leukocyte migration, and suppress seizure activity. These effects suggest potential therapeutic applications in neurodegenerative diseases such as Alzheimer's and Parkinson's, where inflammation and barrier dysfunction are key pathological features.
Classification: D2A Very Toxic Material Causing Other Toxic Effects - Reproductive hazard
E Corrosive Material - Corrosive to skin
Hazard statement(s):
- H318 Causes serious eye damage.
- H361fd Suspected of damaging fertility. Suspected of damaging the unborn child.
Precautionary statement(s):
- P280 Wear protective gloves/ eye protection/ face protection.
- P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Montelukast (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-538)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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