| Field | Specification |
|---|---|
| Target | |
| Alternative names | Apoa1Apolipoprotein A-I ELISA kit; Apo-AI ELISA kit; ApoA-I ELISA kit; Apolipoprotein A1) [Cleaved into: Proapolipoprotein A-I ELISA kit; ProapoA-I); Truncated apolipoprotein A-I] ELISA kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, cell culture supernates, urine, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
apolipoprotein A1(Apo-A1) (APOA1) is a biological molecule commonly studied in cardiovascular research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: Q00623
Biological context
Researchers often monitor apolipoprotein A1(Apo-A1) in serum, plasma, cell culture supernates, and urine to better understand themes such as vascular biology and endothelial function, cardiac remodeling and injury responses, and thrombosis and hemostasis. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in apolipoprotein A1(Apo-A1) may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, endothelial markers, coagulation-related proteins, and cardiac injury markers) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, apolipoprotein A1(Apo-A1) may also appear under names such as Apoa1Apolipoprotein A-I and Apo-AI. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that apolipoprotein A1(Apo-A1) participates in.
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Air pollution is associated with the development of atherosclerosis via the cooperation of CD36 and NLRP3 inflammasome in ApoE-/- mice
Du X.et al,Toxicology Letters,2018
VNN1 Promotes Atherosclerosis Progression in apoE Deficiency Mice Fed a High Fat High Cholesterol Diet
Hu YW.et al,J Lipid Res.,2016
Dihydrocapsaicin Attenuates Plaque Formation through a PPARr/LXRa Pathway in apoE-/- Mice Fed a High-Fat/High-Cholesterol Diet
Yan-Wei Hu et al,PLOS ONE,2013
Cyanidin-3-O-ß-glucoside upregulates hepatic cholesterol 7a-hydroxylase expression and reduces hypercholesterolemia in mice
Dongliang Wang et al,Molecular Nutrition & Food Research,2012
