| Field | Specification |
|---|---|
| Target | |
| Alternative names | Gzmb ELISA kit; Ctla-1 ELISA kit; Ctla1Granzyme B(G,H ELISA kit; EC 3.4.21.79 ELISA kit; CTLA-1 ELISA kit; Cytotoxic cell protease 1 ELISA kit; CCP1 ELISA kit; Fragmentin-2 ELISA kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
granzyme B (GZMB) is a biological molecule commonly studied in cell biology research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: P04187
Biological context
Researchers often monitor granzyme B (GZMB) in serum, plasma, and tissue homogenates to better understand themes such as signal transduction pathways, cell cycle control, and stress-response programs. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in granzyme B (GZMB) may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, phosphorylation-dependent signaling nodes, stress markers, and organelle proteins) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, granzyme B (GZMB) may also appear under names such as Gzmb and Ctla-1. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that granzyme B (GZMB) participates in.
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