| Field | Specification |
|---|---|
| Target | |
| Alternative names | N-terminal procollagen 3 propeptide(P3NP), N-terminal procollagen III propeptide(PIIINP) |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, cell culture supernates, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
N-terminal procollagen Ⅲ propeptide(PⅢNP) is a biological molecule commonly studied in others research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
Biological context
Researchers often monitor N-terminal procollagen Ⅲ propeptide(PⅢNP) in serum, plasma, cell culture supernates, and tissue homogenates to better understand themes such as mechanistic biology studies, biomarker-focused profiling, and disease-model research. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in N-terminal procollagen Ⅲ propeptide(PⅢNP) may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, complementary pathway markers and controls appropriate to the biological model) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, N-terminal procollagen Ⅲ propeptide(PⅢNP) may also appear under names such as N-terminal procollagen 3 propeptide(P3NP), and N-terminal procollagen III propeptide(PIIINP). When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that N-terminal procollagen Ⅲ propeptide(PⅢNP) participates in.
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A cyclic peptide-grafted Fc with hepatocyte growth factor functionality ameliorates hepatic fibrosis in a non-alcoholic steatohepatitis mouse model
NM Rojas,/,2024
Association of novel markers of liver disease with neonatal liver disease in premature baboons, Papio sp.
LM Keller,PLoS One,2020
Cordyceps cicadae NTTU 868 mycelium prevents CCl4-induced hepatic fibrosis in BALB/c mice via inhibiting the expression
Bo-JunKe.et al,Journal of Functional Foods,2018
