| Field | Specification |
|---|---|
| Target | |
| Alternative names | Ntn1Netrin-1 ELISA Kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
Netrin-1(NTN1) is a biological molecule commonly studied in neuroscience research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: O09118
Biological context
Researchers often monitor Netrin-1(NTN1) in serum, plasma, and tissue homogenates to better understand themes such as neuronal signaling and synaptic function, neuroinflammation, and neurodegeneration models. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in Netrin-1(NTN1) may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, synaptic proteins, neurotrophic factors, and neuroinflammatory markers) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, Netrin-1(NTN1) may also appear under names such as Ntn1Netrin-1. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that Netrin-1(NTN1) participates in.
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Netrin-1 co-cross-linked hydrogel accelerates diabetic wound healing in situ by modulating macrophage heterogeneity and promoting angiogenesis
F Shu,Bioactive materials,2024
An imbalance of netrin-1 and DCC during nigral degeneration in experimental models and patients with Parkinson's disease
Y Fan,researchsquare,2022
Netrin-1 Ameliorates Postoperative Delirium-like Behavior in Aged Mice by Suppressing Neuroinammation and Restoring Impaired Blood Brain Barrier Permeability
K Li,Research Square,2020
Macrophage-Specific in Vivo Gene Editing Using Cationic Lipid-Assisted Polymeric Nanoparticles
Luo YL.et al,ACS Nano,2018
Relation between serum levels of chemotaxis-related factors and the presence of coronary artery calcification as expression of subclinical atherosclerosis
Muoz JC.et al,Clin Biochem,2017
