| Field | Specification |
|---|---|
| Target | |
| Alternative names | Pik3ca ELISA Kit; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform ELISA Kit; PI3-kinase subunit alpha ELISA Kit; PI3K-alpha ELISA Kit; PI3Kalpha ELISA Kit; PtdIns-3-kinase subunit alpha ELISA Kit; EC 2.7.1.153 ELISA Kit; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha ELISA Kit; PtdIns-3-kinase subunit p110-alpha ELISA Kit; p110alpha ELISA Kit; Phosphoinositide-3-kinase catalytic alpha polypeptide ELISA Kit; Serine/threonine protein kinase PIK3CA ELISA Kit; EC 2.7.11.1 ELISA Kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
Phosphotylinosital 3 kinase (PIK3CA) is a biological molecule commonly studied in cancer research. Enzymes influence signaling and metabolism through catalytic activity that can shift with physiology and disease states.
UniProt: P42337
Biological context
Researchers often monitor Phosphotylinosital 3 kinase in serum, plasma, and tissue homogenates to better understand themes such as tumor microenvironment biology, cell proliferation and apoptosis, and metastasis and invasion pathways. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in Phosphotylinosital 3 kinase may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, cell-cycle regulators, invasion/ECM markers, and immune-oncology mediators) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, Phosphotylinosital 3 kinase may also appear under names such as Pik3ca and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that Phosphotylinosital 3 kinase participates in.
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