| Field | Specification |
|---|---|
| Target | |
| Alternative names | Tlr4 ELISA Kit; Lps ELISA Kit; Toll-like receptor 4 ELISA Kit; EC 3.2.2.6 ELISA Kit; CD antigen CD284 ELISA Kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
Soluble Toll-like Receptor 4 (TLR4) is a biological molecule commonly studied in immunology research. Receptors mediate cellular responses to ligands and can be regulated through expression, shedding, and internalization.
UniProt: Q9QUK6
Biological context
Researchers often monitor Soluble Toll-like Receptor 4 in serum, plasma, and tissue homogenates to better understand themes such as innate and adaptive immune responses, cytokine signaling networks, and host–pathogen interactions. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in Soluble Toll-like Receptor 4 may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, cytokines, chemokines, acute-phase proteins, and immune-cell activation markers) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, Soluble Toll-like Receptor 4 may also appear under names such as Tlr4 and Lps. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that Soluble Toll-like Receptor 4 participates in.
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Acute and Enduring Sex-Dependent Effects of Pubertal Antimicrobial and Lipopolysaccharide Treatments on Cellular Mechanisms and Behaviours Associated With neurodegeneration
P Esposito,Université d'Ottawa,2024
The enduring effects of antimicrobials and lipopolysaccharide on the cellular mechanisms and behaviours associated with neurodegeneration in pubertal male and female CD1 mice
P Esposito, E Dubé-Zinatelli, M Gandelman, E Liu,Neuroscience,2024
Disulfiram alleviates pristane-induced lupus via inhibiting GSDMD-mediated pyroptosis
L Zhuang,Cell death discovery,2022
Toll-like receptor 4 protects against stress-induced ulcers via regulation of glucocorticoid production in mice
Liang Wang.et al,Stress ,2016
Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice
Golec M et al,Pathol Biol (Paris),2015
Covalently grafted BMP-7 peptide to reduce macrophage/monocyte activity: An in vitro study on cobalt chromium alloy
Tan HC et al,Biotechnol Bioeng,2013
