| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C24H28N2O2 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
MX107 is a selective, potent survivin inhibitor that suppresses proliferation of triple-negative breast cancer (TNBC) cells. It induces degradation of survivin and inhibitor-of-apoptosis proteins (IAPs), thereby inhibiting DNA-damage-induced activation of nuclear factor κB (NF-κB), and it enhances the tumoricidal efficacy of genotoxic treatments when combined with chemotherapeutic drugs[1]. It has the molecular formula C24H28N2O2 and a molecular weight of 376.49 g/mol.
Physical & Chemical Properties
| CAS Number | 2170102-50-6 |
|---|---|
| Molecular Formula | C24H28N2O2 |
| Molecular Weight | 376.49 g/mol |
| SMILES | OC1=C2N=CC=CC2=C(COCC3=CC=C(CC)C=C3)C=C1CN4CCCC4 |
| Signaling Pathway | Apoptosis; NF-κB |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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