| Field | Specification |
|---|---|
| Target | |
| Alternative names | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2, MLC-2v)|Cardiac myosin light chain 2|Myosin light chain 2, slow skeletal/ventricular muscle isoform (MLC-2s/v)|Ventricular myosin light chain 2|MYL2|MLC2 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | myosin, light chain 2, regulatory, cardiac, slow |
| Conjugate | |
| Molecular weight | |
| Purity | |
| Purification | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
MYL2, also named as MLC-2v and MLC-2, is ventricular/cardiac muscle isoform. Defects in MYL2 are the cause of cardiomyopathy familial hypertrophic type 10 (CMH10). Defects in MYL2 are the cause of cardiomyopathy familial hypertrophic with mid-left ventricular chamber type 2 (MVC2). MYL2 has been widely used as a marker of mature ventricular cardiomyocytes.
Product Overview
This monoclonal antibody (clone 1F7), raised in Mouse, recognizes MYL2. It is validated for ELISA, Western Blot, Immunohistochemistry, Immunofluorescence.
Validated Applications
| Applications | ELISA, Western Blot, Immunohistochemistry, Immunofluorescence |
|---|---|
| WB | 1:1000-1:5000 |
| IHC | 1:100-1:1000 |
| IF | 1:50-1:500 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
myosin, light chain 2, regulatory, cardiac, slow
Specifications
| Host | Mouse |
|---|---|
| Clonality | Monoclonal |
| Clone | 1F7 |
| Isotype | IgG2a |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Immunogen | myosin, light chain 2, regulatory, cardiac, slow |
| Purification | Protein A+G Purification |
| Purity | ≥95% as determined by SDS-PAGE |
| Form | Liquid |
| Target MW | 19 kDa |
| UniProt # | P10916 |
| Gene ID | 4633 |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Alternative Names | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2, MLC-2v)|Cardiac myosin light chain 2|Myosin light chain 2, slow skeletal/ventricular muscle isoform (MLC-2s/v)|Ventricular myosin light chain 2|MYL2|MLC2 |
Reactivity Notes
Validated reactivity: Human, Mouse, Rat. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for MYL2 research from Fine Test, or contact us for alternative formats.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
