| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Source | Endogenous metabolite |
| Molecular weight | |
| Molecular formula | C8H14NNa2O9P |
| Purity | |
| Activity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
N-Acetyl-α-D-glucosamine 1-phosphate disodium (GlcNAc-1-P) is an ectopic sugar phosphate and a key intermediate in N-glycoprotein biosynthesis. It also serves as a metabolic precursor of teichoic acid and muramic acid, both components of bacterial cell walls[1]. It is supplied as a white to off-white solid (C8H14NNa2O9P, MW 345.15) at 99.92% purity.
Physical & Chemical Properties
| CAS Number | 31281-59-1 |
|---|---|
| Molecular Formula | C8H14NNa2O9P |
| Molecular Weight | 345.15 g/mol |
| Purity | 99.92% |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | CC(N[C@H]1[C@H](O[C@@H]([C@H]([C@@H]1O)O)CO)OP(O[Na])(O[Na])=O)=O |
| Signaling Pathway | Metabolic Enzyme/Protease |
| Bioactivity Class | Microbial Metabolite |
| Initial Source | Endogenous metabolite |
| Solubility | In Vitro: H2O: 125 mg/mL (362.16 mM; Requires sonication) |
| Storage | -20°C, sealed storage, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
[1]. Olivier Gaurat, et al. A concise synthesis of C-glycosyl phosphate and phosphonate analogues of N-acetyl-α-D-glucosamine 1-phosphate. Tetrahedron Letters Volume 41, Issue 8, 19 February 2000, Pages 1187-1189.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| H2O | 125 mg/mL (362.16 mM) | requires sonication |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); sealed storage, away from moisture; avoid repeated freeze-thaw cycles.
If water is used as the stock solvent, dilute to the working solution and sterilize it through a 0.22 μm filter before use.
Data provided by the manufacturer.
In Vitro
N-glycoprotein biosynthesis involves N-acetyl-α-d-glucosamine 1-phosphate disodium as a key intermediate. N-acetyl-α-d-glucosamine 1-phosphate disodium acts as a metabolic precursor of teichoic acid and muramic acid, both components of bacterial cell walls[1].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
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