| Field | Specification |
|---|---|
| Target | |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C9H14ClNO2 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
N-Methyldopamine hydrochloride is a precursor of adrenaline in the adrenal medulla and a modified form of dopamine (DA) that retains agonist activity at the DA1 receptor. It remains capable of universal surface coating and of secondary reactions through its surface catechols, and it can be applied in heart failure research[1][2][3]. It is supplied as a light brown to gray solid (C9H14ClNO2, MW 203.67) at 99.12% purity.
Physical & Chemical Properties
| CAS Number | 62-32-8 |
|---|---|
| Molecular Formula | C9H14ClNO2 |
| Molecular Weight | 203.67 g/mol |
| Purity | 99.12% |
| Appearance | Solid |
| Color | Light brown to gray |
| SMILES | CNCCC1=CC(O)=C(O)C=C1.Cl |
| Target | D 1 Receptor |
| Signaling Pathway | GPCR/G Protein; Neuronal Signaling |
| Solubility | In Vitro: H2O: ≥ 100 mg/mL (490.99 mM) * "≥" means soluble, but saturation unknown. |
| Storage | 4°C, sealed storage, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| H2O | ≥ 100 mg/mL (490.99 mM) | — |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); sealed storage, away from moisture; avoid repeated freeze-thaw cycles.
If water is used as the stock solvent, dilute to the working solution and sterilize it through a 0.22 μm filter before use.
Data provided by the manufacturer.
In Vitro
N-Methyldopamine hydrochloride has markedly improved surface coating properties and a faster coating rate. Coatings of N-Methyldopamine hydrochloride allow cells to adhere to solid surfaces, and the coating can also be postfunctionalized[1].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
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N-Methyldopamine and ibopamine can prevent chemically-induced oxidative ferroptosis in vitro and in vivo. J Pharmacol Exp Ther 2025 Jul;392(7):103620. PMID: 40570548
