N2-Phenoxyacetylguanosine

SKU:BHB21901896
Overview
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N2-Phenoxyacetylguanosine (CAS 119824-66-7) is a nucleoside/nucleotide analog. Relevant to Cell Cycle/DNA Damage research. Molecular formula C18H19N5O7, molecular weight 417.37 g/mol.
CAS Number 119824-66-7
Molecular Weight 417.37 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-154506-250MG 250 mg
HY-154506-500MG 500 mg
HY-154506-1G 1 g
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 250 mg, 500 mg, 1 g
  • Lead time: shown per option in the variant selector.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 119824-66-7
Applications
  • Functional Assay (In Vitro)
Molecular weight 417.37
Molecular formula C18H19N5O7
SMILES O[C@H]1[C@@H](O)[C@H](N2C(N=C(NC(COC3=CC=CC=C3)=O)NC4=O)=C4N=C2)O[C@@H]1CO
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-154506
Main SKU BHB21901896
Nucleoside & Nucleotide Analogs

Compound Overview

N2-Phenoxyacetylguanosine is classified among the guanosine analogs, a class in which some members display immunostimulatory activity and, in certain animal models, induce type I interferons to generate antiviral effects, with functional activity shown to depend on Toll-like receptor 7 (TLR7) activation[1]. It has a molecular formula of C18H19N5O7 and a molecular weight of 417.37 g/mol.

Physical & Chemical Properties

CAS Number 119824-66-7
Molecular Formula C18H19N5O7
Molecular Weight 417.37 g/mol
SMILES O[C@H]1[C@@H](O)[C@H](N2C(N=C(NC(COC3=CC=CC=C3)=O)NC4=O)=C4N=C2)O[C@@H]1CO
Signaling Pathway Cell Cycle/DNA Damage
Solubility In Vitro: DMSO: 100 mg/mL (239.60 mM; Requires sonication; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

In Vitro

SolventSolubilityNotes
DMSO100 mg/mL (239.60 mM)requires sonication; use freshly opened DMSO (absorbed moisture lowers solubility)

Data provided by the manufacturer.

Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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