nAChR modulator-2

SKU:BHB21901223
Overview
Click light‑blue chips for details
nAChR modulator-2 (CAS 1700657-87-9) is a bioactive small molecule. Relevant to Membrane Transporter/Ion Channel and Neuronal Signaling research. Molecular formula C12H8ClN3O2, molecular weight 261.66 g/mol.
CAS Number 1700657-87-9
Molecular Weight 261.66 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-145300-50MG 50 mg
HY-145300-100MG 100 mg
HY-145300-250MG 250 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 mg, 100 mg, 250 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 1700657-87-9
Applications
  • Functional Assay (In Vitro)
Molecular weight 261.66
Molecular formula C12H8ClN3O2
SMILES O=C1[N-][N+]2=C(CC3=CN=C(C=C3)Cl)C=CC=C2O1
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-145300
Main SKU BHB21901223
Bioactive Small Molecules

Compound Overview

nAChR modulator-2 is an insecticide that acts as an orthosteric modulator of the insect nicotinic acetylcholine receptor (nAChR)[1]. It has a molecular formula of C12H8ClN3O2 and a molecular weight of 261.66 g/mol.

Physical & Chemical Properties

CAS Number 1700657-87-9
Molecular Formula C12H8ClN3O2
Molecular Weight 261.66 g/mol
SMILES O=C1[N-][N+]2=C(CC3=CN=C(C=C3)Cl)C=CC=C2O1
Signaling Pathway Membrane Transporter/Ion Channel; Neuronal Signaling
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.

[1]. Mark Montgomery, et al. Structural Biology-Guided Design, Synthesis, and Biological Evaluation of Novel Insect Nicotinic Acetylcholine Receptor Orthosteric Modulators. J Med Chem. 2022 Feb 10;65(3):2297-2312.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

In Vitro

nAChR modulator-2 inhibits three major pests, with EC90 values of 200 mg/L against larvae of the banded cucumber beetle Diabrotica balteata, 3.12 mg/L against the green peach aphid M. persicae, and 200 mg/L against the cotton leafworm Spodoptera littoralis[1].

Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

Get a Quote

Please use this form for bulk quantity requests or customized products.

Contact Information

Product Information

Try Celltrypse Free – Request Your Sample Today

Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today

Try Celltrypse Free – Request Your Sample Today

Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today