Naloxone HCl

SKU:BHB11900408
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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Naloxone HCl is a research-grade small-molecule antagonist of Opioid Receptor. Supplied as a white crystalline powder with >98% purity (CAS 357-08-4, MW 363.8) dissolvable in DMSO; store at -20°C. For research use only.
Cas No. 357-08-4
Molecular Formula C19H21NO4 • HCl
Purity >98% (HPLC); NMR (Conforms)
Application Notes Opioid Receptor Antagonist
Options selector
Catalog no. Size
SIH-620-100MG 100 mg
SIH-620-500MG 500 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size (2) — 100 mg, 500 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: ships at ambient temperature.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No SIH-620
Activity
  • Antagonist
Alternative Names 5α)-4,5-Epoxy-3,14-dihydro-17-(2-propenyl)morphinan-6-one, hydrochloride
Cas No. 357-08-4
Form White crystalline powder
Molecular Weight 363.8
Product Type
  • Biochemicals
  • Small Molecules
Purity >98% (HPLC); NMR (Conforms)
Shipping Shipped Ambient
SMILES C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl
Solubility May be dissolved in DMSO (35 mg/ml); water (30 mg/ml)
Source Synthetic
Storage -20ºC

Naloxone HCl is a pan-opioid receptor antagonist widely used in clinical settings for opioid overdose reversal. Beyond its emergency applications, Naloxone is being explored in neuroscience for its ability to modulate opioid receptor-mediated signaling. It has been studied in models of pruritus, wound healing, and neuroimmune interactions, offering insights into the role of opioid receptors in neuroinflammation and neurodegenerative disease mechanisms.

Classification: Warning.

Hazard Statements:

H302

Precautionary Statements:

P264 - P270 - P301 + P312 - P501

Naloxone HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-620)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

1. Le Bourdonnec B.,et al. (2008)Bioorg. Med. Chem. Lett. 18:2006.
2. EW., Boyer (2012) New Engl. J. Med. 367:146.
3. WangY., et al. (2017) Transl. Res. 185:13.
4. Wright FL., and RJ Rodgers (2013) Psychopharmacology (Berl.) 226:415.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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