Neboglamine

SKU:BHB21900348
Overview
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Neboglamine (CAS 163000-63-3) is a N-methyl-D-aspartate inhibitor. Relevant to Membrane Transporter/Ion Channel and Neuronal Signaling research. Molecular formula C13H24N2O3, molecular weight 256.34 g/mol. Also known as CR-2249 and XY-2401.
CAS Number 163000-63-3
Molecular Weight 256.34 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-114753-5MG 5 mg
HY-114753-10MG 10 mg
HY-114753-25MG 25 mg
HY-114753-50MG 50 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 5 mg, 10 mg, 25 mg, 50 mg
  • Lead time: made to order; typically ships within 2–3 weeks.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
Alternative names CR-2249; XY-2401
CAS no. 163000-63-3
Applications
  • Functional Assay (In Vitro)
Molecular weight 256.34
Molecular formula C13H24N2O3
SMILES OC(CC[C@H](N)C(NC1CCC(C)(CC1)C)=O)=O
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-114753
Main SKU BHB21900348
Inhibitors

Compound Overview

Neboglamine (CR-2249; XY-2401) is a modulator of the N-methyl-D-aspartate (NMDA) receptor. It increases levels of fos-like immunoreactivity (FLI)-positive cells in the prefrontal cortex, nucleus accumbens, and lateral septal nucleus in rat models, restores NMDA-mediated neurotransmitter release, and inhibits phencyclidine-induced hyperlocomotion[1].

It has the molecular formula C13H24N2O3, MW 256.34.

Physical & Chemical Properties

CAS Number 163000-63-3
Molecular Formula C13H24N2O3
Molecular Weight 256.34 g/mol
SMILES OC(CC[C@H](N)C(NC1CCC(C)(CC1)C)=O)=O
Signaling Pathway Membrane Transporter/Ion Channel; Neuronal Signaling
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Chiusaroli R, et al., Antipsychotic-like effects of the N-methyl-D-aspartate receptor modulator neboglamine: an immunohistochemical and behavioural study in the rat. Pharmacol Res. 2010 May;61(5):430-6.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.How long does this take to ship?
A.This item is produced on request and typically ships within 2–3 weeks.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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