Neramexane mesylate

SKU:BHB21901084
Overview
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Neramexane mesylate (CAS 457068-92-7) is an antagonist. Relevant to Membrane Transporter/Ion Channel and Neuronal Signaling research. Molecular formula C12H27NO3S, molecular weight 265.41 g/mol.
CAS Number 457068-92-7
Molecular Weight 265.41 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-138973A-50MG 50 mg
HY-138973A-100MG 100 mg
HY-138973A-250MG 250 mg
Available Options

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  • Options: Size: 50 mg, 100 mg, 250 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 457068-92-7
Applications
  • Functional Assay (In Vitro)
Molecular weight 265.41
Molecular formula C12H27NO3S
SMILES NC1(CC(C)(CC(C)(C1)C)C)C.CS(=O)(O)=O
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-138973A
Main SKU BHB21901084
Antagonists

Compound Overview

Neramexane mesylate acts as an antagonist at both α9α10 nicotinic acetylcholine receptors and N-methyl-D-aspartate (NMDA) receptors. It can improve moderate to severe tinnitus and has been reported to exhibit neuroprotective effects[1]. The compound has the molecular formula C12H27NO3S and a molecular weight of 265.41 g/mol.

Physical & Chemical Properties

CAS Number 457068-92-7
Molecular Formula C12H27NO3S
Molecular Weight 265.41 g/mol
SMILES NC1(CC(C)(CC(C)(C1)C)C)C.CS(=O)(O)=O
Signaling Pathway Membrane Transporter/Ion Channel; Neuronal Signaling
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Suckfüll M, et al. A randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of neramexane in patients with moderate to severe subjective tinnitus. BMC Ear Nose Throat Disord. 2011;11:1. Published 2011 Jan 11.

[2]. Sukhotina IA, et al. Caffeine withdrawal syndrome in social interaction test in mice: effects of the NMDA receptor channel blockers, memantine and neramexane. Behav Pharmacol. 2004;15(3):207-214.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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