| Field | Specification |
|---|---|
| Target | |
| Alternative names | CDKL3; NKIAMRE; Cyclin-dependent kinase-like 3; Serine/threonine-protein kinase NKIAMRE |
| Gene ID | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CDKL3. AA range:291-340 |
| Conjugate | |
| Concentration | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes NKIAMRE. It is validated for Immunohistochemistry, Immunofluorescence, Western Blot, ELISA.
Validated Applications
| Applications | Immunohistochemistry, Immunofluorescence, Western Blot, ELISA |
|---|---|
| WB 1 | 500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
The antiserum was produced against synthesized peptide derived from human CDKL3. AA range:291-340
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Rat, Mouse |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CDKL3. AA range:291-340 |
| Concentration | 1 mg/mL |
| Observed Band | 67kD |
| Subcellular Location | Cytoplasm . |
| Swiss-Prot | Q8IVW4 |
| Gene ID | 51265 |
| Storage | -20°C/1 year |
Reactivity Notes
Validated reactivity: Human, Rat, Mouse. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for NKIAMRE research from ELK Biotechnology, or contact us for alternative formats.
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