NLRP3-IN-23

SKU:BHB21902286
Overview
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NLRP3-IN-23 is an inhibitor. Relevant to Immunology/Inflammation research. Molecular formula C24H36O3Si, molecular weight 400.63 g/mol.
Molecular Weight 400.63 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-157146-50MG 50 mg
HY-157146-100MG 100 mg
HY-157146-250MG 250 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 mg, 100 mg, 250 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
Applications
  • Functional Assay (In Vitro)
Molecular weight 400.63
Molecular formula C24H36O3Si
SMILES O=C(C=C1[Si](C)(CCCCCC)C)C([C@@H]2C=C(C)CC[C@H]2C(C)=C)=C(O)C1=O
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-157146
Main SKU BHB21902286
Inhibitors

Compound Overview

NLRP3-IN-23 inhibits heme-mediated induction of the NLRP3 inflammasome. At a concentration of 0.1 μM, it significantly suppresses this heme-mediated induction[1]. The compound has the molecular formula C24H36O3Si and a molecular weight of 400.63 g/mol.

Physical & Chemical Properties

Molecular Formula C24H36O3Si
Molecular Weight 400.63 g/mol
SMILES O=C(C=C1[Si](C)(CCCCCC)C)C([C@@H]2C=C(C)CC[C@H]2C(C)=C)=C(O)C1=O
Signaling Pathway Immunology/Inflammation
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Shete S S, et al. Sila-CBD Derivatives as Inhibitors of Heme-Induced NLRP3 Inflammasome: Application in Hemolytic Diseases[J]. ACS Medicinal Chemistry Letters, 2023.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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