| Field | Specification |
|---|---|
| Target | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Recombinant protein of human NME1 |
| Conjugate | |
| Purification | |
| Concentration | |
| Storage | |
| Storage buffer | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes NME1. It is validated for Western Blot.
Validated Applications
| Applications | Western Blot |
|---|---|
| WB | 1:1000-1:5000 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
Recombinant protein of human NME1
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Recombinant protein of human NME1 |
| Purification | Affinity Purification |
| Concentration | 0.5 mg/mL |
| Storage Buffer | PBS with 0.05% sodium azide and 50% glycerol, pH 7.4 |
| Calculated MW | 17kDa |
| UniProt # | P15531 |
| Lead Time | 2-3 business days |
| Validity | 12 months |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice packs |
| Target Synonyms | AWD;AWD;drosophila;homolog of;GAAD;Granzyme A activated DNase;Granzyme A-activated DNase;GZMA activated DNase;Metastasis inhibition factor NM23;NB;NBS;NDK A;NDKA;NDKA;NDP kinase A;NDPK-A;NDPKA;NM23;NM23 long variant;included;nm23-H1;NM23-M1;NM23H1B;included;NME/NM23 nucleoside diphosphate kinase 1;Nme1;NME1-NME2 spliced read-through transcript;included;Non-metastatic cells 1;protein (NM23A) expres |
Reactivity Notes
Validated reactivity: Human, Mouse, Rat. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for NME1 research from Elabscience Biotechnology Co Ltd, or contact us for alternative formats.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
