| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | ARA267; KMT3B; H3-K36-HMTase; H4-K20-HMTase; Lysine N-methyltransferase 3B |
| Conjugate | |
| Formulation | |
| Host | |
| Immunogen | Recombinant protein of human NSD1. |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage |
Product Overview
Research Use OnlyThe nuclear receptor-binding SET domain-containing protein 1 (NSD1) belongs to a family of proteins which have all been implicated in human malignancy. The protein family includes NSD2 and NSD3, both of which show 70-75% sequence identity with NSD1 but contribute substantially less to overgrowth phenotypes. Defects and microdeletions of the NSD1 gene are involved in Sotos syndrome, childhood acute myeloid leukemia (AML), Weaver syndrome and Beckwith-Wiedemann Syndrome (BWS).
Validated Applications
| Western Blot (WB) | 500 - 1:1000 |
|---|
Key Specifications
| Host Species | Rabbit |
|---|---|
| Species Reactivity | Human, Mouse |
| Conjugate | Unconjugated |
| Purification | Affinity Purification |
| Formulation | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
| Molecular Weight | ~ 297 kDa |
| Catalog No. | BS71397 |
| UniProt | Q96L73 |
| Alternative Names | ARA267; KMT3B; H3-K36-HMTase; H4-K20-HMTase; Lysine N-methyltransferase 3B |
Immunogen / Antigen
Recombinant protein of human NSD1.
Reactivity Notes
NSD1 polyclonal antibody detects endogenous levels of NSD1 protein.
Storage & Handling
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Safety
For Research Use Only (RUO). Not intended for diagnostic, therapeutic, or veterinary use. Handle according to standard laboratory biosafety guidelines. Avoid skin and eye contact. Dispose of waste in accordance with local regulations.
This antibody has been validated for: Western Blot. For each application, follow the recommended dilutions on the product datasheet and optimize empirically for your sample type.
WB 1:500 - 1:1000
This antibody has been confirmed reactive against: Human, Mouse. Cross-reactivity with other species may occur due to sequence homology but is not guaranteed without independent validation.
Recombinant protein of human NSD1.
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Avoid repeated freeze-thaw cycles. Centrifuge vials briefly before opening. Dilute immediately before use.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
