NTRK1/NTRK3/NTRK2 Recombinant Monoclonal Antibody

Overview

This is a monoclonal anti-NTRK1/NTRK3/NTRK2 antibody raised in Rabbit, with confirmed utility in ELISA, IHC. It is designed to detect NTRK1/NTRK3/NTRK2 protein in Human and supports researchers working in others contexts.

Key elements and design rationale

• Immunogen: A synthesized peptide from human NTRK1/NTRK3/NTRK2 protein — determines the epitope region; confirm compatibility with sample preparation and expected post-translational modifications.
• Host species (Rabbit): Requires anti-rabbit-IgG secondary reagents for indirect detection.
• Monoclonal format: Single-epitope binding provides high specificity and lot-to-lot reproducibility. Confirm epitope accessibility under your assay conditions.
• Isotype (IgG): Matched secondary antibodies and isotype controls required. Compatible with standard Protein A/G purification workflows.
• Purification (Affinity chromatography): Enriches for specific immunoglobulin classes; reduces non-specific background vs. crude antisera.

Biological background

NTRK1/NTRK3/NTRK2 (also referred to as gp140trk antibody, High affinity nerve growth factor receptor antibody, High affinity nerve growth factor receptor precursor antibody, MTC antibody, Neurotrophic tyrosine kinase receptor type 1 antibody, NTRK1 antibody, NTRK1_HUMAN antibody, Oncogene TRK antibody, p14-TrkA antibody, p140 TrkA antibody, p140-TrkA antibody, Slow nerve growth antibody, Trk A antibody, TRK antibody, Trk-A antibody, TRK1 antibody, TRK1-transforming tyrosine kinase protein antibody, Tropomyosin-related kinase A antibody, Tyrosine kinase receptor A antibody, Tyrosine kinase receptor antibody, EC 2.7.10.1 antibody, ETS related protein neurotrophic receptor tyrosine kinase fusion antibody, ETS related protein neurotrophic receptor tyrosine kinase fusion protein antibody, ETV6 NTRK3 fusion antibody, GP145 TrkC antibody, gp145(trkC) antibody, GP145-TrkC antibody, GP145TrkC antibody, Neurotrophic tyrosine kinase receptor type 3 antibody, Neurotrophin 3 receptor antibody, NT 3 growth factor receptor antibody, NT 3 growth factor receptor precursor antibody, NT 3 receptor antibody, NT-3 growth factor receptor antibody, Ntrk3 antibody, NTRK3_HUMAN antibody, OTTHUMP00000192915 antibody, TRK C antibody, Trk-C antibody, TRKC antibody, TrkC tyrosine kinase antibody, Tyrosine kinase receptor C antibody, AI848316 antibody, BDNF tropomyosine receptor kinase B antibody, BDNF/NT 3 growth factors receptor antibody, BDNF/NT-3 growth factors receptor antibody, Brain derived neurotrophic factor receptor antibody, C030027L06Rik antibody, EC 2.7.10.1 antibody, GP145 TrkB antibody, GP145-TrkB antibody, GP145-TrkB/GP95-TrkB antibody, GP95 TrkB antibody, Neurotrophic receptor tyrosine kinase 2 antibody, Neurotrophic tyrosine kinase receptor type 2 antibody, Neurotrophin receptor tyrosine kinase type 2 antibody, NTRK 2 antibody, Ntrk2 antibody, NTRK2_HUMAN antibody, Obesity, hyperphagia, and developmental delay, included antibody, RATTRKB1 antibody, Tkrb antibody, Trk B antibody, Trk-B antibody, TRKB antibody, TrkB tyrosine kinase antibody, TRKB1 antibody, Tropomyosin related kinase B antibody, tyrosine kinase receptor B antibody, Tyrosine receptor kinase B antibody) is a protein target studied in Human systems. Expression, subcellular localization, and post-translational modifications vary across cell types and disease states — factors critical to antibody-based detection design. Consult UniProt, NCBI Gene, and primary literature for current annotation of NTRK1/NTRK3/NTRK2 biology in others.

Common research applications

• ELISA: Quantification of soluble target in biological fluids or culture supernatants. Ensure samples are within the linear detection range.
• IHC: Visualization of target in FFPE or frozen tissue sections. Optimize antigen retrieval and secondary detection for each tissue type.

Notes for experimental interpretation

• Isotype controls: Use an isotype-matched (IgG from Rabbit) control at equivalent concentration to assess non-specific background.
• Cross-reactivity: Confirm the clone does not cross-react with related family members under your assay conditions.
• Matrix effects: Sample matrix can affect performance; pilot dilution linearity and spike-recovery experiments are advised for quantitative studies.
• Species reactivity: Confirmed for Human. Extrapolation to untested species requires empirical validation.

This product is a recombinant monoclonal antibody expressed in HEK293F cells.

• Datasheet (12946083)

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.