| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 9,10-Deepithio-9,10-didehydroacanthifolicin |
| Cas No. | |
| Form | White crystalline solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in chloroform, ethanol, methanol, acetone or ethyl acetate |
| Source | Synthetic |
| Storage |
Okadaic acid is a potent and selective inhibitor of protein phosphatases PP1 and PP2A, enzymes critical to cellular signaling and homeostasis. Widely used in neuroscience research, Okadaic acid induces tau hyperphosphorylation and neurofibrillary tangle formation, mimicking key features of Alzheimer's disease pathology. As such, it serves as a valuable tool for modeling neurodegeneration and studying the molecular mechanisms underlying tauopathies and other neurodegenerative disorders.
Classification: Acute toxicity, Oral (Category 3), H301
Acute toxicity, Inhalation (Category 3), H331
Acute toxicity, Dermal (Category 3), H311
Skin irritation (Category 2), H315
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard statements:
- H301 + H311 + H331 Toxic if swallowed, in contact with skin or if inhaled
- H315 Causes skin irritation
Precautionary statements:
- P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
- P264 Wash skin thoroughly after handling.
- P270 Do not eat, drink or smoke when using this product.
- P271 Use only outdoors or in a well-ventilated area.
- P280 Wear protective gloves/ protective clothing.
- P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician.
- P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
- P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
- P312 Call a POISON CENTER or doctor/ physician if you feel unwell.
- P322 Specific measures (see supplemental first aid instructions on this label).
- P330 Rinse mouth.
- P332 + P313 If skin irritation occurs: Get medical advice/ attention.
- P361 Remove/Take off immediately all contaminated clothing.
- P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
- P405 Store locked up.
- P501 Dispose of contents/ container to an approved waste disposal plant
Okadaic acid (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-521)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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