Oleamide

Oleamide is an endogenous fatty acid amide originally identified in the cerebrospinal fluid of sleep-deprived animals. It acts as a neuromodulator with agonist activity at cannabinoid CB1 receptors and also activates PPARγ. Oleamide exhibits neuroprotective properties, including anti-inflammatory and vasodilatory effects. It has been shown to attenuate neuronal damage and systemic inflammation in various disease models. Its multifaceted actions on neurotransmission, inflammation, and vascular tone make it a compound of interest in neuroscience, particularly in the context of sleep regulation, neuroinflammation, and neurodegeneration.

Classification: Warning

GHS Hazard Statements:

H315, H317, H319, H335, H413

Precautionary Statement Codes:

P261, P264, P264+P265, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Oleamide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-627)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

• Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
• Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
• Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
• QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
• Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).