Olmesartan impurity

SKU:BHB21900891
Overview
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Olmesartan impurity (CAS 154709-18-9) is an antagonist supplied as a solid. Reported to act on AT1 Receptor. Relevant to GPCR/G Protein research. Molecular formula C33H26N4O, molecular weight 494.59 g/mol.
CAS Number 154709-18-9
Molecular Weight 494.59 g/mol
Form Solid
Target AT1 Receptor
Storage 4°C as supplied; in solvent -80°C
Options selector
Catalog no. Size
HY-133775-5MG 5 mg
HY-133775-10MG 10 mg
HY-133775-25MG 25 mg
HY-133775-50MG 50 mg
HY-133775-100MG 100 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg
  • Lead time: shown per option in the variant selector.
  • Storage: 4°C, stored under nitrogen. In solvent: -80°C, 6 months; -20°C, 1 month (stored under nitrogen).
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: refrigerate at 4°C as soon as possible.
Field Specification
Target AT1 Receptor
CAS no. 154709-18-9
Applications
  • Functional Assay (In Vitro)
Molecular weight 494.59
Molecular formula C33H26N4O
SMILES OCC1=CC=C(C2=CC=CC=C2C3=NN=NN3C(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)C=C1
Form Solid
Storage 4°C, stored under nitrogen. In solvent: -80°C, 6 months; -20°C, 1 month (stored under nitrogen).
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-133775
Main SKU BHB21900891
Antagonists

Compound Overview

Olmesartan impurity is an impurity of Olmesartan. Olmesartan, also known as RNH-6270, is an antagonist of the angiotensin II receptor (AT1R) and has potential relevance for high blood pressure research[1][2]. This impurity is supplied as a white to off-white solid (C33H26N4O, MW 494.59).

Physical & Chemical Properties

CAS Number 154709-18-9
Molecular Formula C33H26N4O
Molecular Weight 494.59 g/mol
Appearance Solid
Color White to off-white
SMILES OCC1=CC=C(C2=CC=CC=C2C3=NN=NN3C(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)C=C1
Target AT1 Receptor
Signaling Pathway GPCR/G Protein
Storage 4°C, stored under nitrogen. In solvent: -80°C, 6 months; -20°C, 1 month (stored under nitrogen).
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Yanagihara H, et al. Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet. J Pharmacol Sci. 2016 Jul;131(3):190-7.

[2]. Tanno T, et al. Olmesartan Inhibits Cardiac Hypertrophy in Mice Overexpressing Renin Independently of Blood Pressure: Its Beneficial Effects on ACE2/Ang(1-7)/Mas Axis and NADPH Oxidase Expression. J Cardiovasc Pharmacol. 2016 Jun;67(6):503-9.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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