| Field | Specification |
|---|---|
| Alternative names | 10-Ethenyl-19-norprogesterone |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C22H30O2 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Org OD 02-0, also known as 10-Ethenyl-19-norprogesterone, is a specific agonist of the membrane progesterone receptor α (mPRα), with an IC50 of 33.9 nM. It activates MAPK activity and inhibits prolactin (PRL) secretion in the pituitary[1][2]. It is supplied as a white to off-white solid (C22H30O2, MW 326.47) at 99.7% purity.
Physical & Chemical Properties
| CAS Number | 13258-85-0 |
|---|---|
| Molecular Formula | C22H30O2 |
| Molecular Weight | 326.47 g/mol |
| Purity | 99.7% |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | CC([C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C=C)[C@@]3([H])CC[C@]12C)=O)=O |
| Signaling Pathway | Vitamin D Related/Nuclear Receptor; MAPK/ERK Pathway |
| Solubility | In Vitro: DMSO: 24 mg/mL (73.51 mM; Requires sonication and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Ethanol: 3.3 mg/mL (10.11 mM; Requires sonication and warming) |
| Storage | Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Biological Activity
Activity & Target
33.9 nM (mPRα)[1]
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| DMSO | 24 mg/mL (73.51 mM) | requires sonication and warming; use freshly opened DMSO (absorbed moisture lowers solubility) |
| Ethanol | 3.3 mg/mL (10.11 mM) | requires sonication and warming |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); avoid repeated freeze-thaw cycles.
Data provided by the manufacturer.
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