| Field | Specification |
|---|---|
| Applications | |
| Molecular weight | |
| Molecular formula | C69H102N12O16S |
| Activity | |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
OSu-Glu-VC-PAB-MMAD is an agent-linker conjugate for ADC applications with potent antitumor activity, combining the potent tubulin inhibitor MMAD with the cleavable ADC linker OSu-Glu-VC-PAB. It has the molecular formula C69H102N12O16S and a molecular weight of 1387.68 g/mol.
Physical & Chemical Properties
| Molecular Formula | C69H102N12O16S |
|---|---|
| Molecular Weight | 1387.68 g/mol |
| SMILES | O=C(CCC1=O)N1OC(CCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(N3[C@H]([C@H](OC)[C@@H](C)C(N[C@@H](CC4=CC=CC=C4)C5=NC=CS5)=O)CCC3)=O)=O)=O)=O)C=C2)=O)=O)=O)=O |
| Signaling Pathway | Cytoskeleton; Cell Cycle/DNA Damage; Antibody-Drug Conjugate/ADC Related |
| Bioactivity Class | Auristatin |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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