| Field | Specification |
|---|---|
| Target | |
| Alternative names | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1|Csk-binding protein|Transmembrane adapter protein PAG|Transmembrane phosphoprotein Cbp|PAG1|CBP|PAG |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | phosphoprotein associated with glycosphingolipid microdomains 1 |
| Conjugate | |
| Molecular weight | |
| Purity | |
| Purification | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
Negatively regulates TCR(T-cell antigen receptor)-mediated signaling in T-cells and FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes PAG1. It is validated for ELISA, Western Blot.
Validated Applications
| Applications | ELISA, Western Blot |
|---|---|
| WB | 1:500-1:2000 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
phosphoprotein associated with glycosphingolipid microdomains 1
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse |
| Immunogen | phosphoprotein associated with glycosphingolipid microdomains 1 |
| Purification | Immunogen Affinity Purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Form | Liquid |
| Target MW | 50-60 kDa |
| UniProt # | Q9NWQ8 |
| Gene ID | 55824 |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Alternative Names | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1|Csk-binding protein|Transmembrane adapter protein PAG|Transmembrane phosphoprotein Cbp|PAG1|CBP|PAG |
Reactivity Notes
Validated reactivity: Human, Mouse. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for PAG1 research from Fine Test, or contact us for alternative formats.
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