Pazopanib

SKU:BHB11900289
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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Pazopanib is a research-grade small-molecule inhibitor of Tyrosine kinase supporting Cell Signaling and Cancer research. Supplied as a white solid powder with >98% purity (CAS 444731-52-6, MW 437.5) soluble in DMSO, not in water; store at -20°C. For research use only.
Cas No. 444731-52-6
Molecular Formula C21H23N7O2S
Purity >98%
Application Notes Tyrosine kinase inhibitor
Options selector
Catalog no. Size
SIH-506-5MG 5 mg
SIH-506-25MG 25 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size (2) — 25 mg, 5 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: ships at ambient temperature.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Alternative names 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide
CAS no. 444731-52-6
Applications
  • Functional Assay (In Vitro)
Source Synthetic
Molecular weight 437.5
Molecular formula C21H23N7O2S
Purity >98%
Bioactivity Inhibitor
Activity
  • Inhibitor
Solubility Soluble in DMSO, not in water
SMILES CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N
InChIKey CUIHSIWYWATEQL-UHFFFAOYSA-N
Form White solid powder
Storage -20ºC
Shipping Shipped Ambient
Catalog no. (Mfr.) SIH-506
Main SKU BHB11900289

Pazopanib is a multi-targeted tyrosine kinase inhibitor primarily used in oncology to inhibit angiogenesis via the HGF/c-MET and VEGF pathways. While its direct application in neuroscience is limited, its anti-angiogenic and anti-inflammatory properties may offer therapeutic potential in neuro-oncology and neuroinflammatory conditions. Ongoing research is exploring its role in modulating the tumor microenvironment in brain cancers such as glioblastoma.

Classification: Not a hazardous substance or mixture.

Safety Phrases:

  • S22 - Do not breathe dust.
  • S24/25 - Avoid contact with skin and eyes.
  • S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

Pazopanib (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-506)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

1. Outani H., et al. (2014) BMC Cancer. 14: 455.
2. Pick A.M., & Nystrom K.K. (2012) Clin. Ther. 34(3): 511–520.
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