| Field | Specification |
|---|---|
| Alternative names | PegIFN a-2b; Sch 54031; Sylatron; ViraferonPeg |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Purity | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Peginterferon alfa-2b, also known as PegIFN a-2b, Sch 54031, Sylatron, or ViraferonPeg, is an immunomodulator. It is a recombinant alfa-2b interferon covalently linked to PEG, with antiviral activity against HCV, and it decreases viral DNA in HIV. It can be used in research on melanoma and hepatitis C[1][2]. It is supplied as a colorless to light yellow liquid (MW 31 kDa; PEG 12 kDa) at ≥99.0% purity.
Physical & Chemical Properties
| CAS Number | 215647-85-1 |
|---|---|
| Molecular Weight | 31 kDa; PEG 12 kDa g/mol |
| Purity | ≥99.0% |
| Appearance | Liquid |
| Color | Colorless to light yellow |
| Signaling Pathway | Anti-infection |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Formulation | Please refer to the lot-specific COA for specific buffer information. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
Individuals who have cirrhosis from chronic hepatitis C and already have portal hypertension benefit from Peginterferon alfa-2b[1]. By upregulating melanocortin receptors on melanocytes, Peginterferon alfa-2b can induce melanogenesis, which causes the adverse reaction of tongue pigmentation[1].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
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