| Field | Specification |
|---|---|
| Alternative names | (2R)-1-[[5-[(Z)-[5-[[(2,6-Dichlorophenyl)methyl]sulfonyl]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]methyl]-2,4-dimethyl-1H-pyrrol-3-yl]carbonyl]-2-(1-pyrrolidinylmethyl)pyrrolidine |
| CAS no. | |
| Applications | |
| Source | Synthetic |
| Molecular weight | |
| Molecular formula | C32H34Cl2N4O4S |
| Purity | |
| Bioactivity | Inhibitor |
| Activity | |
| Solubility | Soluble to 100 mM in DMSO. |
| SMILES | |
| InChIKey | |
| Form | Yellow solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
PHA 665752 is a selective inhibitor of the c-Met receptor tyrosine kinase, which is involved in cell growth, survival, and motility. In neuroscience, c-Met signaling plays a role in neurodevelopment, synaptic plasticity, and response to injury. PHA 665752 is used to investigate the impact of c-Met inhibition on neuronal regeneration and neuroinflammation. Dysregulation of c-Met pathways has been implicated in neurodegenerative diseases and brain tumors. By modulating receptor activity, PHA 665752 contributes to understanding the molecular mechanisms of neural repair and disease progression.
Classification: Not WHMIS controlled.
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
PHA-665752 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-421)
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