Phenylbutyrate Na

Sodium phenylbutyrate is a small molecule with multiple mechanisms of action, including histone deacetylase inhibition, glutamine scavenging, and modulation of protein folding. In neuroscience, it has been shown to reduce tau pathology in Alzheimer's disease models, inhibit glioma cell proliferation, and enhance neuroprotective gene expression. Its ability to cross the blood-brain barrier and modulate epigenetic and metabolic pathways makes it a promising candidate for treating neurodegenerative and neurodevelopmental disorders.

Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.

Safety Phrases:

• S22 - Do not breathe dust
• S24/25 - Avoid contact with skin and eyes
• S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Phenylbutyrate Na (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-255)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

• Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
• Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
• Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
• QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
• Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

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Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).