| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | (2S,3R,4R)-Octadecane-1,2,3,4-tetraol |
| Cas No. | |
| Form | White powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 2 mg/ml in ethanol |
| Source | Isolated from Saccharomyces cerevisiae |
| Storage |
Phytosphingosine is a naturally occurring sphingoid base found in yeast, plants, and animals, noted for its role in cellular stress responses. In neuroscience, it has garnered interest for its pro-apoptotic effects in cancer cells and potential modulation of neuronal survival pathways. Phytosphingosine activates the p38 MAPK signaling cascade, leading to cytochrome c release and caspase-3 activation—mechanisms relevant to programmed cell death and neurodegeneration. Its involvement in stress-induced signaling suggests potential applications in studying neuronal injury and neuroinflammation. While not yet a mainstream neurotherapeutic, its biochemical profile makes it a valuable tool in neurodegenerative disease models exploring apoptosis and stress responses.
Classification: Not WHMIS controlled.
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Phytosphingosine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-524)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
