| Field | Specification |
|---|---|
| Target | |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C27H32N8O4Se |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
PI3Kδ-IN-18 is a selective inhibitor of PI3Kδ with an IC50 value below 0.1 nM. It can be used in autoimmune research[1]. It has the molecular formula C27H32N8O4Se and a molecular weight of 611.55 g/mol.
Physical & Chemical Properties
| CAS Number | 3019965-38-6 |
|---|---|
| Molecular Formula | C27H32N8O4Se |
| Molecular Weight | 611.55 g/mol |
| SMILES | COC1=NC=C(C2=CC=C(N=CN=C3N[C@@H]4CN(C([C@@H](NC(OC(C)(C)C)=O)C[Se]C)=O)CC4)C3=N2)C=C1C#N |
| Target | PI3Kδ |
| Signaling Pathway | PI3K/Akt/mTOR |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Biological Activity
IC50 & Target
|
PI3Kδ 0.1 nM (IC50) |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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