PIM-IN-2

SKU:BHB21902331
Overview
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PIM-IN-2 (CAS 1006699-45-1) is an inhibitor. Reported to act on PIM2. Relevant to JAK/STAT Signaling research. Molecular formula C19H22N4O2, molecular weight 338.40 g/mol.
CAS Number 1006699-45-1
Molecular Weight 338.40 g/mol
Target PIM2
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-160006-50MG 50 mg
HY-160006-100MG 100 mg
HY-160006-250MG 250 mg
Available Options

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  • Options: Size: 50 mg, 100 mg, 250 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
Target PIM2
CAS no. 1006699-45-1
Applications
  • Functional Assay (In Vitro)
Molecular weight 338.40
Molecular formula C19H22N4O2
SMILES OC(/C=C/C1=CC=CC(C2=NC(NCC3CCNCC3)=CN=C2)=C1)=O
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-160006
Main SKU BHB21902331
Inhibitors

Compound Overview

PIM-IN-2, also known as Pim-2, is a Pim kinases inhibitor with an IC50 of 25 nM. It promotes cell survival, is antiapoptotic, and has shown elevated expression in a variety of human tumors[1]. It has the molecular formula C19H22N4O2 and a molecular weight of 338.40 g/mol.

Physical & Chemical Properties

CAS Number 1006699-45-1
Molecular Formula C19H22N4O2
Molecular Weight 338.40 g/mol
SMILES OC(/C=C/C1=CC=CC(C2=NC(NCC3CCNCC3)=CN=C2)=C1)=O
Target PIM2
Signaling Pathway JAK/STAT Signaling
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Qian K, et al. Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode [J]. Journal of medicinal chemistry, 2009, 52(7): 1814-1827.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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