| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C29H44Cl2N6O16P4 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Piperaquine tetraphosphate is a potent antimalarial agent that shows inhibitory activity against both chloroquine-sensitive and chloroquine-resistant isolates. In combination with dihydroartemisinin, it has potential for research into chloroquine-resistant malaria[1][2]. It has the molecular formula C29H44Cl2N6O16P4 and a molecular weight of 927.49 g/mol.
Physical & Chemical Properties
| CAS Number | 911061-10-4 |
|---|---|
| Molecular Formula | C29H44Cl2N6O16P4 |
| Molecular Weight | 927.49 g/mol |
| SMILES | ClC1=CC=C2C(N3CCN(CCCN4CCN(C5=CC=NC6=CC(Cl)=CC=C56)CC4)CC3)=CC=NC2=C1.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O |
| Signaling Pathway | Anti-infection |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
In Vitro
Piperaquine tetraphosphate is highly active against all Cameroonian isolates, with an IC50 of 38.9 nM (range, 7.76-78.3 nM), and inhibits both chloroquine-sensitive and chloroquine-resistant isolates[1].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
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bioRxiv. 2025 Oct 17.
