| Field | Specification |
|---|---|
| Applications | |
| Molecular weight | |
| Molecular formula | C29H31NO10S2 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
PKM2 activator 6 activates PKM2 (Kd 121 μM) and inhibits PDK1 (Kd 19.6 μM). It induces apoptosis in colorectal cells inhibits their proliferation and migration, and suppresses glycolysis. It inhibits proliferation of DLD-1, HCT-8, HT-29 and MCF-10A cells with IC50 values of 10.04, 2.16, 3.57 and 66.39 μM, respectively[1]. It has a molecular formula of C29H31NO10S2 and a molecular weight of 617.69 g/mol.
Physical & Chemical Properties
| Molecular Formula | C29H31NO10S2 |
|---|---|
| Molecular Weight | 617.69 g/mol |
| SMILES | O=C(OC)C(CS[C@@H](C(C1=O)=CC(C2=C1C(O)=CC=C2O)=O)C/C=C(C)\C)NC(C3=CC(S(=O)(C)=O)=CC=C3OC)=O |
| Signaling Pathway | Metabolic Enzyme/Protease; PI3K/Akt/mTOR |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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