| Field | Specification |
|---|---|
| Target | |
| Alternative names | Pleckstrin homology domain-containing family F member 1 (PH domain-containing family F member 1)|Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains (Apoptosis-inducing protein)|PH and FYVE domain-containing protein 1|Phafin-1|Zinc finger FYVE domain-containing protein 15|PLEKHF1|APPD|LAPF|ZFYVE15 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | pleckstrin homology domain containing, family F(with FYVE domain) member 1 |
| Conjugate | |
| Molecular weight | |
| Purity | |
| Purification | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane(LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization(MMP) resulting in the release of PDCD8.
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes PLEKHF1. It is validated for ELISA, Western Blot, Immunofluorescence, Immunohistochemistry.
Validated Applications
| Applications | ELISA, Western Blot, Immunofluorescence, Immunohistochemistry |
|---|---|
| WB | 1:500-1:1000 |
| IHC | 1:20-1:200 |
| IF | 1:10-1:100 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
pleckstrin homology domain containing, family F(with FYVE domain) member 1
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse |
| Immunogen | pleckstrin homology domain containing, family F(with FYVE domain) member 1 |
| Purification | Immunogen Affinity Purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Form | Liquid |
| Target MW | 31 kDa |
| UniProt # | Q96S99 |
| Gene ID | 79156 |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Alternative Names | Pleckstrin homology domain-containing family F member 1 (PH domain-containing family F member 1)|Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains (Apoptosis-inducing protein)|PH and FYVE domain-containing protein 1|Phafin-1|Zinc finger FYVE domain-containing protein 15|P |
Reactivity Notes
Validated reactivity: Human, Mouse. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for PLEKHF1 research from Fine Test, or contact us for alternative formats.
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