(±)17(18)-EpETE-Ethanolamide

SKU:BHB20446412
Overview
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(±)17(18)-EpETE-Ethanolamide (CAS 2123491-23-4) is a small molecule inhibitor supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Small Molecule Inhibitor
CAS No. 2123491-23-4
Molecular Weight
Form Solid
Shipping Room Temperature
Options selector
Catalog no. Size
T85120-10MG 10 mg
T85120-50MG 50 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 10 mg, 50 mg
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No T85120
Activity
  • Small Molecule Inhibitor
Cas No. 2123491-23-4
Product Type
  • Small Molecule Inhibitor
Signaling Pathway Others
Target Others

Compound Overview

(±)17(18)-EpETE-Ethanolamide (CAS 2123491-23-4) is a research-grade small molecule supplied by TargetMol.

Physical Properties

CAS Number 2123491-23-4
Form Solid
Shipping Room Temperature (RT)

Biological Activity

(±)17(18)-EpETE-Ethanolamide, an omega-3 endocannabinoid epoxide, originates from eicosapentaenoic ethanolamide (EPEA) through cytochrome P450 (CYP) epoxygenases action and is decomposed by soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FA, AH). Its endogenous synthesis occurs in LPS-stimulated and EPEA-supplemented BV-2 microglia cells, a process inhibited by the CYP inhibitor ketoconazole. This compound mitigates IL-6 and nitrite levels while enhancing IL-10 production following LPS exposure in BV-2 microglia. At a dose of 50 uM, it prevents platelet aggregation caused by arachidonic acid but not that triggered by ADP, collagen, or ristocetin. Additionally, it facilitates the dilation of constricted bovine coronary arteries (ED50= 1.1 uM) and blocks VEGF-driven tubulogenesis in human microvascular endothelial cells (HMVECs).

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

Can inhibitors be used for animal experiments?

Yes, our inhibitors can be used for animal/in vivo experiments. However, some compounds may not have literature supporting their use in animal experiments. In such cases, we cannot guarantee efficacy.

How do you ensure the quality and purity of compounds?

The structure of compounds is confirmed through HNMR and purity is verified through HPLC or LCMS, with most compounds having a purity of over 98%. Each batch comes with a Certificate of Analysis (COA), and testing reports are also displayed on our official website.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

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Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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