| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C27H35NO6 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
(+)-Tuberine is an alkaloid found in Haplophyllum tuberculatum, with antibacterial and antifungal activities. It can be used in studies on antimicrobial natural products and microbial growth inhibition[1]. It has a molecular formula of C27H35NO6 and a molecular weight of 469.58 g/mol.
Physical & Chemical Properties
| CAS Number | 97400-75-4 |
|---|---|
| Molecular Formula | C27H35NO6 |
| Molecular Weight | 469.58 g/mol |
| SMILES | [C@](OC(C)=O)(C)(C)[C@H]1O[C@@]([C@@H](COC2=CC=C(CCNC(=O)C3=CC=CC=C3)C=C2)O)(C)CC1 |
| Signaling Pathway | Anti-infection |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
In Vitro
In the disk diffusion assay, (+)-Tuberine (0.1, 1 μg/mL; 37°C; 24-48 h) suppresses the growth of S. aureus, B. subtilis, and E. coli; at 1 μg/mL, the inhibition zones measure 10-15 mm against S. aureus and B. subtilis and 2-5 mm against E. coli[1]. In the liquid culture plate count assay, (+)-Tuberine (1 μg/mL; 37°C; 24 h) significantly suppresses B. subtilis and S. aureus growth, bringing both below 106 CFU/mL at 24 h, but has only weak inhibitory effects on E. coli[1]. In turbidity assays, (+)-Tuberine (0.1, 1 μg/mL; 37°C; 12 h) suppresses B. subtilis, E. coli, and S. aureus, with inhibition rates of 84%, 48%, and 85% at 0.1 μg/mL and 86%, 50%, and 94% at 1 μg/mL[1]. In the disc diffusion assay, (+)-Tuberine (0.1, 1 μg/mL; 37°C; 24-48 h) suppresses the growth of S. cerevisiae, with an inhibition zone of 6-10 mm at 1 μg/mL[1]. In liquid culture plate counting assays, (+)-Tuberine (1 μg/mL; 37°C; 24 h) inhibits the growth of S. cerevisiae[1]. In turbidity assays, (+)-Tuberine (0.1, 1 μg/mL; 37°C; 12 h) gives inhibition rates of 84% and 91% against S. cerevisiae[1].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
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