| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A synthesized peptide derived from human PNK / PNKP was used as the immunogen for the PNKP antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
PNKP Antibody / Polynucleotide kinase 3 phosphatase is an antibody targeting PNKP. Host: Rabbit. Monoclonal. Clone: 30P00. Format: Liquid. Applications: WB, IHC, IP.
Key elements and design rationale
- Target: PNKP.
- Immunogen: A synthesized peptide derived from human PNK / PNKP was used as the immunogen for the PNKP antibody..
- Species reactivity: Human.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
PNKP antibody detects polynucleotide kinase 3'-phosphatase, a DNA repair enzyme with dual kinase and phosphatase activities. PNKP processes DNA ends by phosphorylating 5' termini and dephosphorylating 3' termini, preparing them for ligation during single-strand and double-strand break repair.
Common research applications
- WB: relative abundance and band pattern assessment using appropriate controls.
- IHC: tissue distribution assessment; interpret with matched controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
