POP-IN-2

SKU:BHB21901184
Overview
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POP-IN-2 (CAS 2743432-81-5) is an inhibitor. Relevant to Metabolic Enzyme/Protease research. Molecular formula C24H33BN2O5, molecular weight 440.34 g/mol.
CAS Number 2743432-81-5
Molecular Weight 440.34 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-143475-50MG 50 mg
HY-143475-100MG 100 mg
HY-143475-250MG 250 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 mg, 100 mg, 250 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 2743432-81-5
Applications
  • Functional Assay (In Vitro)
Molecular weight 440.34
Molecular formula C24H33BN2O5
SMILES CC(NC1=CC=C(C(N2C(B3O[C@@]4([H])[C@@]([C@](C5)([H])C(C)(C)[C@]5([H])C4)(C)O3)CCC2)=O)C(OC)=C1)=O
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-143475
Main SKU BHB21901184
Inhibitors

Compound Overview

POP-IN-2 is a potent, covalent prolyl oligopeptidase (POP) inhibitor with a Ki of 6 nM. It can be used for studying neurodegenerative diseases and cancer[1]. It has the molecular formula C24H33BN2O5 and a molecular weight of 440.34 g/mol.

Physical & Chemical Properties

CAS Number 2743432-81-5
Molecular Formula C24H33BN2O5
Molecular Weight 440.34 g/mol
SMILES CC(NC1=CC=C(C(N2C(B3O[C@@]4([H])[C@@]([C@](C5)([H])C(C)(C)[C@]5([H])C4)(C)O3)CCC2)=O)C(OC)=C1)=O
Signaling Pathway Metabolic Enzyme/Protease
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Biological Activity

IC50 & Target

IC50: 6 nM (POP)[1]

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Jessica Plescia, et al. Discovery of covalent prolyl oligopeptidase boronic ester inhibitors. Eur J Med Chem. 2020 Jan 1;185:111783.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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