| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C25H33ClN6O3 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
PPACK II is an irreversible and specific inhibitor of glandular and plasma kallikreins[1]. It has the molecular formula C25H33ClN6O3 and a molecular weight of 501.02 g/mol.
Physical & Chemical Properties
| CAS Number | 74392-49-7 |
|---|---|
| Molecular Formula | C25H33ClN6O3 |
| Molecular Weight | 501.02 g/mol |
| SMILES | N=C(N)NCCC[C@@H](C(CCl)=O)NC([C@@H](NC([C@H](N)CC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O |
| Signaling Pathway | Immunology/Inflammation |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
In Vitro
PPACK II (0.62-50 μg/mL) significantly inhibits proteolysis of B-type natriuretic peptide (BNP)[2].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
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