| Field | Specification |
|---|---|
| Applications | |
| Molecular weight | |
| Molecular formula | C23H29N7O |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
PRMT4-IN-2 is a pan-inhibitor of protein arginine methyltransferases (PRMTs), with IC50 values of 92 nM against PRMT4, 436 nM against PRMT6, 460 nM against PRMT1, 823 nM against PRMT8 and 1.386 μM against PRMT3[1]. It has a molecular formula of C23H29N7O and a molecular weight of 419.52 g/mol.
Physical & Chemical Properties
| Molecular Formula | C23H29N7O |
|---|---|
| Molecular Weight | 419.52 g/mol |
| SMILES | O=C(N[C@@H]1CN(CCNC)CC1)C2=CC3=NC=NC(NC4=CC=C(CN)C=C4)=C3C=C2 |
| Signaling Pathway | Epigenetics |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Biological Activity
IC50 & Target
IC50: 92 nM (PRMT4), 436 nM (PRMT6), 460 nM (PRMT1), 823 nM (PRMT8), 1.386 μM (PRMT3)[1]
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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