Prothipendyl hydrochloride

SKU:BHB21900405
Overview
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Prothipendyl hydrochloride (CAS 1225-65-6) is an enzyme substrate supplied as a solid. Relevant to Metabolic Enzyme/Protease research. Molecular formula C16H20ClN3S, molecular weight 321.87 g/mol.
Purity 99.94%
CAS Number 1225-65-6
Molecular Weight 321.87 g/mol
Form Solid
Storage Room temperature; in solvent -80°C
Options selector
Catalog no. Size
HY-116780A-5MG 5 mg
HY-116780A-10MG 10 mg
HY-116780A-50MG 50 mg
HY-116780A-1MLX10MM 1 mL x 10 mM (in DMSO)
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 5 mg, 10 mg, 50 mg, 1 mL x 10 mM (in DMSO)
  • Lead time: varies by selected option.
  • Storage: Store at room temperature, keep dry and cool. In solvent: -80°C, 1 year; -20°C, 6 months.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store at room temperature.
Field Specification
CAS no. 1225-65-6
Applications
  • Functional Assay (In Vitro)
Molecular weight 321.87
Molecular formula C16H20ClN3S
Purity 99.94%
SMILES CN(C)CCCN1C2=C(C=CC=C2)SC3=CC=CN=C13.Cl
Form Solid
Storage Store at room temperature, keep dry and cool. In solvent: -80°C, 1 year; -20°C, 6 months.
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-116780A
Main SKU BHB21900405
Enzyme Substrates

Compound Overview

Prothipendyl hydrochloride is a tricyclic azaphenothiazine neuroleptic agent that is a substrate of the CYP isozymes CYP1A2, CYP2D6, CYP2C19, and CYP3A4. It has sedating and psychomotorically damping effects and can be used for research on psychomotoric agitation, sleep disorder, and anxiety[1]. It is supplied as a light yellow to yellow solid (C16H20ClN3S, MW 321.87) at 99.94% purity.

Physical & Chemical Properties

CAS Number 1225-65-6
Molecular Formula C16H20ClN3S
Molecular Weight 321.87 g/mol
Purity 99.94%
Appearance Solid
Color Light yellow to yellow
SMILES CN(C)CCCN1C2=C(C=CC=C2)SC3=CC=CN=C13.Cl
Signaling Pathway Metabolic Enzyme/Protease
Solubility In Vitro: DMSO: 100 mg/mL (310.68 mM; Requires sonication; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Storage Store at room temperature, keep dry and cool. In solvent: -80°C, 1 year; -20°C, 6 months.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. J F FLEETWOOD, et al. The Treatment of Mental Symptoms in the Aged With Prothipendyl (Tolnate). J Coll Gen Pract. 1964 Sep;8(2):262-6.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.

In Vitro

SolventSolubilityNotes
DMSO100 mg/mL (310.68 mM)requires sonication; use freshly opened DMSO (absorbed moisture lowers solubility)

Aliquot the stock solution and store it at -80°C (up to 1 year) or -20°C (up to 6 months); avoid repeated freeze-thaw cycles.

Data provided by the manufacturer.

Q.Why is there no price on some sizes?
A.Availability and lead time for those sizes are confirmed on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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