| Field | Specification |
|---|---|
| Target | |
| Alternative names | ACAN ELISA Kit; AGC1 ELISA Kit; Aggrecan core protein ELISA Kit; Cartilage-specific proteoglycan core protein ELISA Kit; CSPCP ELISA Kit; Fragment ELISA Kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
Aggrecan core protein(ACAN) is a biological molecule commonly studied in signal transduction research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: Q28670
Biological context
Researchers often monitor Aggrecan core protein(ACAN) in serum, plasma, and tissue homogenates to better understand themes such as mechanistic biology studies, biomarker-focused profiling, and disease-model research. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in Aggrecan core protein(ACAN) may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, complementary pathway markers and controls appropriate to the biological model) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, Aggrecan core protein(ACAN) may also appear under names such as ACAN and AGC1. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that Aggrecan core protein(ACAN) participates in.
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Pilot-scale expression, purification, and bioactivity of recombinant human TGF-β3 from Escherichia coli
MengZhou, et al,European Journal of Pharmaceutical Sciences,2018
