| Field | Specification |
|---|---|
| Alternative names | DL-α-Glycerol phosphate sodium |
| CAS no. | |
| Applications | |
| Source | Endogenous metabolite — Human Gut Microbiota Metabolites |
| Molecular weight | |
| Molecular formula | C3H7Na2O6P |
| Purity | |
| Activity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
(Rac)-sn-Glycerol 3-phosphate sodium, also known as DL-α-Glycerol phosphate sodium, is an A-site substrate analogue. When it is bound to the A-site, the rate of reaction of indole and nucleophilic indole analogues with E(A-A) is strongly inhibited[1]. It is supplied as a white to off-white solid (C3H7Na2O6P, MW 216.04) at 99.95% purity.
Physical & Chemical Properties
| CAS Number | 1555-56-2 |
|---|---|
| Molecular Formula | C3H7Na2O6P |
| Molecular Weight | 216.04 g/mol |
| Purity | 99.95% |
| Appearance | Solid |
| Color | White to off-white |
| Structure Classification | Others |
| SMILES | OC(CO)COP(O[Na])(O[Na])=O |
| Signaling Pathway | Metabolic Enzyme/Protease |
| Bioactivity Class | Human Endogenous Metabolite |
| Initial Source | Endogenous metabolite — Human Gut Microbiota Metabolites |
| Solubility | In Vitro: H2O: 125 mg/mL (578.60 mM; Requires sonication) |
| Storage | 4°C, sealed storage, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| H2O | 125 mg/mL (578.60 mM) | requires sonication |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); sealed storage, away from moisture; avoid repeated freeze-thaw cycles.
If water is used as the stock solvent, dilute to the working solution and sterilize it through a 0.22 μm filter before use.
Data provided by the manufacturer.
In Vitro
Produced as an intermediate of glycolysis, (Rac)-sn-Glycerol 3-phosphate sodium is a glycerol derivative carrying a phosphate group[1]. Through allosteric inhibition, (Rac)-sn-Glycerol 3-phosphate sodium regulates tryptophan synthesis, and it does so by attaching to the α subunit of tryptophan synthase[1]. Microorganisms gain an advantage from (Rac)-sn-Glycerol 3-phosphate sodium where nutrients are scarce, since it supplies phosphorus, carbon and energy. Cultivation of microorganisms is one application of (Rac)-sn-Glycerol 3-phosphate sodium[2]. Metal ions are bound by (Rac)-sn-Glycerol 3-phosphate sodium, which leads to insoluble phosphate minerals. In situ bioremediation aimed at lowering environmental pollution is another application of (Rac)-sn-Glycerol 3-phosphate sodium[2].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
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