| Field | Specification |
|---|---|
| Target | |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
Antithrombin III(AT III)ELISA Kit is a biological molecule commonly studied in cardiovascular research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: Q5M7T5
Biological context
Researchers often monitor Antithrombin III(AT III)ELISA Kit in serum, plasma, and tissue homogenates to better understand themes such as vascular biology and endothelial function, cardiac remodeling and injury responses, and thrombosis and hemostasis. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in Antithrombin III(AT III)ELISA Kit may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, endothelial markers, coagulation-related proteins, and cardiac injury markers) and by keeping pre-analytical variables consistent across groups.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that Antithrombin III(AT III)ELISA Kit participates in.
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Both UFH and NAH alleviate shedding of endothelial glycocalyx and coagulopathy in LPS‑induced sepsis
Huang X, et al,Experimental and Therapeutic Medicine,2019
IKKβ regulates the expression of coagulation and fibrinolysis factors through the NF-κB canonical pathway in LPS-stimulated alveolar epithelial cells type II
Bo Liu, et al,Experimental and Therapeutic Medicine,2019