| Field | Specification |
|---|---|
| Target | |
| Alternative names | Apob ELISA kit; Aa1064 ELISA kit; Ac1-060Apolipoprotein B-100 ELISA kit; Apo B-100) [Cleaved into: Apolipoprotein B-48 ELISA kit; Apo B-48)] ELISA kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
apolipoprotein B100 (Apo-B100) (APOB) is a biological molecule commonly studied in cardiovascular research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: Q7TMA5
Biological context
Researchers often monitor apolipoprotein B100 (Apo-B100) in serum, plasma, and tissue homogenates to better understand themes such as vascular biology and endothelial function, cardiac remodeling and injury responses, and thrombosis and hemostasis. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in apolipoprotein B100 (Apo-B100) may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, endothelial markers, coagulation-related proteins, and cardiac injury markers) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, apolipoprotein B100 (Apo-B100) may also appear under names such as Apob and Aa1064. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that apolipoprotein B100 (Apo-B100) participates in.
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Air pollution is associated with the development of atherosclerosis via the cooperation of CD36 and NLRP3 inflammasome in ApoE-/- mice
Du X.et al,Toxicology Letters,2018
Hypolipidemic and anti-inflammatory effects of aorta and heart tissues of cattle and pigs in the atherosclerosis rat model
Chernukha IM.et al,Anim Sci J,2018
Effect of n-3 PUFA supplementation at different EPA: DHA ratios on the spontaneously hypertensive obese rat model of the metabolic syndrome
Molinar-Toribio E et al,Br J Nutr,2015
