| Field | Specification |
|---|---|
| Target | |
| Alternative names | Ido1 ELISA Kit; Ido ELISA Kit; Indo ELISA Kit; Indoleamine 2,3-dioxygenase 1 ELISA Kit; IDO-1 ELISA Kit; EC 1.13.11.52 ELISA Kit; Indoleamine-pyrrole 2,3-dioxygenase ELISA Kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates, cell lysates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
Indoleamine 2, 3-dioxygenase (IDO1) is a biological molecule commonly studied in metabolism research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: Q9ERD9
Biological context
Researchers often monitor Indoleamine 2, 3-dioxygenase in serum, plasma, tissue homogenates, and cell lysates to better understand themes such as energy homeostasis, glucose and lipid metabolism, and insulin sensitivity and endocrine regulation. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in Indoleamine 2, 3-dioxygenase may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, insulin, adipokines, lipid-transport proteins, and stress-related enzymes) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, Indoleamine 2, 3-dioxygenase may also appear under names such as Ido1 and Ido. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that Indoleamine 2, 3-dioxygenase participates in.
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Human Wharton’s jelly mesenchymal stem cells protect axotomized rat retinal ganglion cells via secretion of anti-inflammatory and neurotrophic factors
JE Millan-Rivero, et al,Scientific Reports,2018
Regulation of the kynurenine metabolism pathway by Xiaoyao San and the underlying effect in the hippocampus of the depressed rat
Jiajia Wang.et al,Journal of Ethnopharmacology,2018
Regulation of the secretion of immunoregulatory factors of mesenchymal stem cells (MSCs) by collagen-based scaffolds during chondrogenesis
Yang J.et al,Materials Science and Engineering: C,2016
Indoleamine 2,3-dioxygenase is upregulated in the brain of rats with acute pancreatitis.
Jiang H.et al,Pancreatology.,2015
